Mathematical Problems in Engineering
Volume 2010 (2010), Article ID 808019, 18 pages
Research Article

Nonlinear Filtering of Oscillatory Measurements in Cardiovascular Applications

School of Engineering and Materials Science, Queen Mary, University of London, London E14NS, UK

Received 5 November 2009; Revised 4 February 2010; Accepted 13 March 2010

Academic Editor: Carlo Cattani

Copyright © 2010 Ranjan Vepa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


An array of nonidentical and locally connected chaotic biological neurons is modelled by a single representative chaotic neuron model based on an extension of the Hindmarsh-Rose neuron. This model is then employed in conjunction with the unscented Kalman filter to study the associated state estimation problem. The archetypal system, which was deliberately chosen to be chaotic, was corrupted with noise. The influence of noise seemed to annihilate the chaotic behaviour. Consequently it was observed that the filter performs quite well in reconstructing the states of the system although the introduction of relatively low noise had a profound effect on the system. Neither the noise-corrupted process model nor the filter gave any indications of chaos. We believe that this behaviour can be generalised and expect that unscented Kalman filtering of the states of a biological neuron is completely feasible even when the uncorrupted process model exhibits chaos. Finally the methodology of the unscented Kalman filter is applied to filter a typical simulated ECG signal using a synthetic model-based approach.