Computational and Mathematical Methods in Medicine
Volume 10 (2009), Issue 3, Pages 203-218
Original Article

Linear Latent Structure Analysis and Modelling of Multiple Categorical Variables

Duke University, Durham, NC, USA

Received 18 July 2007; Accepted 29 May 2008

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Linear latent structure analysis is a new approach for investigation of population heterogeneity using high-dimensional categorical data. In this approach, the population is represented by a distribution of latent vectors, which play the role of heterogeneity variables, and individual characteristics are represented by the expectation of this vector conditional on individual response patterns. Results of the computer experiments demonstrating a good quality of reconstruction of model parameters are described. The heterogeneity distribution estimated from 1999 National Long Term Care Survey (NLTCS) is discussed. A predictive power of the heterogeneity scores on mortality is analysed using vital statistics data linked to NLTCS.